Abstract—The aims of this research was to determine the effect of yoga exercise on MnSOD levels and anthropometric parameters in abdominal obesity populations. Cardiovascular diseases are the main cause of death in the world. Cardiovascular diseases risk factors are abdominal obesity and oxidative stress conditions. Yoga exercise is an effective physical training in correcting these risk factors. Subjects were taken from populations with abdominal obesity in Denpasar Bali Indonesia. Thirty-seven subjects were randomly divided into 2 groups, the yoga group (n = 18) and the control group (n = 19). Yoga exercise was carried out twice a week in 8 weeks. The control group was not given any physical training during the study. We compared the pre-test and post-test results in the two groups. There were significant differences waist/hip ratio (W/H ratio) and MnSOD level (p<0,05). We concluded that yoga exercise has a positive effect on MnSOD levels and W/H ratio in population with abdominal obesity.