Abstract—Syphilis during pregnancy poses a significant threat to both maternal and fetal health and is also linked to considerable psychological distress. This study uses a systematic review to analyze nearly 20 years of Chinese and English literature, examining the psychological impact of syphilis during pregnancy on maternal mental health and exploring effective intervention strategies. The results show that during diagnosis, pregnant women often worry about fetal health, social stigma, and a crisis in maternal identity. During treatment, psychological conflicts can occur due to fear of pain and concerns about medication safety, while postpartum, women may experience prolonged self-blame and anxiety. To address these issues, the study recommends a comprehensive intervention plan, including psychological support and counseling, improved communication between doctors and patients, pain management, social support, long-term follow-up, and interdisciplinary teamwork. These efforts can help reduce psychological stress, improve treatment adherence, and lead to better maternal and fetal outcomes. Future research should explore the effects of cultural differences and promote public education to reduce social stigma. This study provides both theoretical insights and practical guidance for implementing psychological interventions in managing syphilis during pregnancy.
 

Keywords—syphilis during pregnancy, maternal psychology, psychological intervention, treatment ambivalence, maternal and fetal health, social support