Novel Devices for Drug and Gene Delivery
Andreas Loth
Beuth University of Applied Sciences, Berlin, Germany
Abstract—Mechanical standard application devices or methods for intra dermal drug delivery especially for DNA vaccination offer some disadvantages, which will be discussed. Reaching a certain skin layer is often difficult. With a cutting system and a tattoo based hollow needle device, two new technical approaches were developed to overcome several limits and allow an adequate and fast delivery of drugs at a certain depth. The integration of an electroporation electrode enhances the efficiency.
Index Terms—drug delivery, vaccination cutting, electroporation, cannula, electrotattooing
Cite: Andreas Loth, "Novel Devices for Drug and Gene Delivery," International Journal of Pharma Medicine and Biological Sciences, Vol. 4, No. 1, pp. 44-50, January 2015.