Abstract—Tropical eosinophilia, has been known to physicians even prior to 1930. Eosinophilia is said to be when there is increase in absolute eosinophil count by >600/cumm. It can occur due to various pathologic conditions. Tissue eosinophil infiltration is an important feature of tropical pulmonary eosinophilia. Herbal drugs explained in Ayurveda provide a wide range of formulations for the management of such diseases. Present study was conducted to assess the efficacy and safety of an Ayurvedic compound formulation ' Dusparshadi Yog ' in tropical pulmonary eosinophilia. This article accounts the data of 30 patients diagnosed for tropical eosinophilia that underwent a full clinical, radiological, and pathological study and treated with the drug. There was a significant result in eosinophil and neutrophil count along with other criteria resolute for the study including respiration rate, PEFR, etc. (p < 0.001).