1. How to submit my research paper? What’s the process of publication of my paper?
The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or.pdf format to the submission email: ijpmbs@ejournal.net.
You’ll be given a paper number if your submission is successful. Your paper then will undergo peer review process, which may take approximately one and a half months under normal circumstances, three tops.
After blind peer review, you will receive the notification letter with the review result of your paper...
2. Can I submit an abstract?
The journal publishes full research papers.[Read More]
 

Phytochemical Screening and Evaluation of Antioxidant, Antibacterial Activities of Ethanol Extract from Combretum quadrangulare Collected in Vietnam

Tran Thanh Men1, Huynh Kim Yen2, Huynh Thi Cam Lan1, Nguyen Hoang Son3, Do Tan Khang4, and Nguyen Trong Tuan5
1.Department of Biology, College of Natural Sciences, Can Tho University, Cantho City 900000, Vietnam
2.Department of Biology, College of Agriculture and Rural Development, Kien Giang University, Kien Giang Province 91000, Vietnam
3.Department of Chemistry, Faculty of Basic Sciences, Vinh Long University of Technology Education, Vinh Long City, 890000, Vietnam
4.Department of Molecular Biotechnology, Biotechnology Research and Development Institute, Can Tho University, Cantho City, 94000, Vietnam
5.Department of Chemistry, College of Natural Sciences, Can Tho University, Cantho City 900000, Vietnam
AbstractCombretum quadrangulare Kurz has long been considered a precious herb, which is very useful in treating various kinds of diseases on humans and aquatic animals. The study was conducted to evaluate the antioxidant and antibacterial effects of ethanol extracts from Combretum quadrangulare Kurz fruit collected in Kien Giang province, Vietnam. Research results showed that ethanol extract from Combretum quadrangulare Kurz fruit contained bioactive compounds such as alkaloids, flavonoids, steroids and triterpenoids, tannins, and phenolics. In the ethanol extract of Combretum quadrangulare Kurz fruit, the content of total phenolics and total flavonoids were recorded at 230.89 ± 2.36 mg GAE/g extract and 165.35 ± 5.80 mg QE/g extract, respectively. The survey results of in vitro antioxidant capacity through four methods of DPPH, ABTS●+, RP and TAC indicated that the extracts of Combretum quadrangulare Kurz fruit showed its good activity with EC50 values of 103.90 ± 0.40 μg/mL, 24.18 ± 0.06 μg/mL, 128.58 ± 0.20 μg/mL and 79.30 ± 1.40 μg/mL, respectively. The investigation results of in vivo antioxidant activity on fruit fly Drosophila melanogaster model showed that the fruit flies raised in the medium supplemented with 1 mg/mL extract of Combretum quadrangulare Kurz fruit had in vivo antioxidant effect under the conditions of oxidative stress induced by Paraquat and H2O2. In addition, the extract from Combretum quadrangulare Kurz fruit also had the ability to against the bacteria causing diseases in aquatic animals such as Edwardsiella ictaluri, Aeromonas hydrophila and Streptococcus agalactiae.
 
Index Terms—antibacteria, antioxidant, phenolic, flavonoid, Drosophila melanogaster, Combretum quadrangulare

Cite: Tran Thanh Men, Huynh Kim Yen, Huynh Thi Cam Lan, Nguyen Hoang Son, Do Tan Khang, and Nguyen Trong Tuan, "Phytochemical Screening and Evaluation of Antioxidant, Antibacterial Activities of Ethanol Extract from Combretum quadrangulare Collected in Vietnam," International Journal of Pharma Medicine and Biological Sciences, Vol. 11, No. 3, pp. 59-64, July 2022. doi: 10.18178/ijpmbs.11.3.59-64

Copyright © 2022 by the authors. This is an open access article distributed under the Creative Commons Attribution License (CC BY-NC-ND 4.0), which permits use, distribution and reproduction in any medium, provided that the article is properly cited, the use is non-commercial and no modifications or adaptations are made.
Copyright © 2012-2021 International Journal of Pharma Medicine and Biological Sciences, All Rights Reserved
E-mail: ijpmbs@ejournal.net