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Effect of Red Bean (Vigna angularis [Willd] Ohwi & Ohashi) Extract Administration on Lipid Profile, Uric Acid, and Blood Glucose Level in Male White Rat

Benedicta I. Rumagit1, Isworo2, and Donald E. Kalonio1
1.Department of Pharmacy, Manado Health Polytechnic, Manado, Indonesia
2.Department of Nursing, Manado Health Polytechnic, Manado, Indonesia
Abstract—Red bean is a source of fiber, both water-soluble or insoluble, possesses low glycemic index and beneficial for reducing cholesterol and blood glucose. It belongs to nut plants that contain about 50-150 mg of purine. This study aims to know the effect of the red bean (Vigna angularis [Willd] Ohwi & Ohashi) extract administration on lipid profile, such as on male white rat. The type of research used is laboratory experimental research using Postest With Control Group design. Red bean (V. angularis [Willd] Ohwi & Ohashi) was obtained in Manado, North Sulawesi. Parameters measured were total cholesterol, HDL, LDL, triglyceride, uric acid, and blood glucose level of male white rat’s blood after administered red bean extract and high cholesterol-fed for 21 days. Statistical analysis used One Way ANOVA. Results showed that red bean extract administration influenced the lipid profile, could reduce LDL level, and did not increase the uric acid and glucose level. Nevertheless, further study is needed with higher dose variations of the extract and on the effect of high-cholesterol diet, based on its type and administration route.

Index Terms—red beans, lipid profile, blood glucose, uric acid

Cite:Benedicta I. Rumagit, Isworo, and Donald E. Kalonio, "Effect of Red Bean (Vigna angularis [Willd] Ohwi & Ohashi) Extract Administration on Lipid Profile, Uric Acid, and Blood Glucose Level in Male White Rat," International Journal of Pharma Medicine and Biological Sciences, Vol. 8, No. 3, pp. 110-113, July 2019. doi: 10.18178/ijpmbs.8.3.110-113

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