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The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or.pdf format to the submission email: ijpmbs@ejournal.net.
You’ll be given a paper number if your submission is successful. Your paper then will undergo peer review process, which may take approximately one and a half months under normal circumstances, three tops.
After blind peer review, you will receive the notification letter with the review result of your paper...
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The journal publishes full research papers.[Read More]
 

Tissue Distribution of Copper in Mice Following Exposure to Arsenic in Drinking Water

Younghee Kim 1, Jiguk Kim 2, and Kisok Kim 2
1. Department of Skin & Health Care, Suseong College, Daegu, Republic of Korea
2. College of Pharmacy, Keimyung University, Daegu, Republic of Korea
Abstract—Arsenic (As) is a common and conspicuous toxicant. The tissue distribution and correlation between tissues for copper was assessed in male C57Bl/6 mice exposed to 0, 50, 500, or 5000 ppb arsenic in their drinking water for 3 weeks. The copper concentration in blood increased linearly with increasing arsenic doses, whereas the copper concentration in liver or kidney decreased linearly with respect to the dose applied.  These results indicate that there may be tissue difference in the disturbed levels of copper in the mice blood, liver, and kidney by subchronic exposure to arsenic in drinking water.
 
Index Terms—arsenic, copper, drinking water, mice

Cite:Younghee Kim, Jiguk Kim, and Kisok Kim"Tissue Distribution of Copper in Mice Following Exposure to Arsenic in Drinking Water," International Journal of Pharma Medicine and Biological Sciences, Vol. 7, No. 3, pp. 63-66, July 2018. doi: 10.18178/ijpmbs.7.3.63-66
 

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