1. How to submit my research paper? What’s the process of publication of my paper?
The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or.pdf format to the submission email: ijpmbs@ejournal.net.
You’ll be given a paper number if your submission is successful. Your paper then will undergo peer review process, which may take approximately one and a half months under normal circumstances, three tops.
After blind peer review, you will receive the notification letter with the review result of your paper...
2. Can I submit an abstract?
The journal publishes full research papers.[Read More]
 

Thermal Damage Modeling Analysis and Validation during Treatment of Tissue Tumors

Mhamed Nour, Aziz Oukaira, Mohammed Bougataya, and Ahmed Lakhssassi
Computer Engineering Department, University of Quebec in Outaouais Gatineau, (PQ), 18X 3X7, Canada
Abstract—The objective of the Laser Interstitial Thermal Therapy (LITT) in treatment is the maximization of the therapeutic effects (tumor tissue laser ablation) with the minimization of any side effects (damage to healthy tissue). The big challenge is the approximation of the tissue tumor topology. While using the MRI stack to capture the 3D tissue tumor topology, a software for conversion to 3d stl file can be used, but the result is always far away from the real topology of the tissue tumor. Mathematical models will help us predict the temperature distribution and tissue damage during the dosimetry planning phase. These models need to be validated with real data in order to be accepted and used by physicians in the dosimetry planning. This paper describes a modeling analysis approach for the prediction of laser ablation volume during the planning phase. Three different COMSOL implementations of thermal damage during the Laser Interstitial Thermal Therapy in Treatment of tissue tumors were proposed and validated with real data to confirm the validity of these models. A prediction damage formulation is generated and implemented as a Field-Programmable Gate Array (FPGA). The final product of these implementations is expected to be used by physician as apps during the planning of the dosimetry

Index Terms—biomedical informatics, computational biology, laser interstitial thermal therapy, laser ablation, dosimetry planning

Cite:Mhamed Nour, Aziz Oukaira, Mohammed Bougataya, and Ahmed Lakhssassi"Thermal Damage Modeling Analysis and Validation during Treatment of Tissue Tumors," International Journal of Pharma Medicine and Biological Sciences, Vol. 6, No. 4, pp. 98-104, October 2017. doi: 10.18178/ijpmbs.6.4.98-104
Copyright © 2012-2015 International Journal of Pharma Medicine and Biological Sciences, All Rights Reserved
E-mail: ijpmbs@ejournal.net