Abstract—This research study about anastomosis configuration of end-to-side brachioaxillary arteriovenous graft (AV graft) by comparing flow pattern of different angles, i.e., 20°, 30°, 45°, and 90° at the anastomosis sites. The study assumption is that the angle of anastomosis relate to intimal hyperplasia at inner vessel wall. The AV graft models were constructed by Computational fluid dynamics (CFD) analysis. Since the shear stress are an initiator and modulator of intimal hyperplasia (IH). Flow pattern and corresponding wall shear stress are analyzed. The result shows that the anastomosis with small angle is more proper to use than large angle in order to reduce intimal hyperplasia at inner vessel wall which decrease the incidence of stenosis. Also the rate of AV graft reoperation will be decrease.