Abstract—In the study to assess the effect of selected strengthening exercises on functional status among patients with Chronic Kidney Disease, 30 subjects were selected by using non probability convenience sampling technique. Modified functional status questionnaire was used to assess the functional status of subjects before and after intervention. The intervention was performance of selected strengthening exercises by each subject for 20 min twice a day in the morning and evening in the presence of the investigator from day 1 to day 13. Post test was done on day 14. On comparison of functional status among subjects before and after intervention, the computed ‘t’ value (2.38) was greater than table value (2.05) at 0.05 level of significance. There was statistically significant increase in the functional status of subjects after selected strengthening exercises (p=0.05). There was statistically significant increase in each parameters of functional status ie, Basic activities of daily living, Instrumental activities of daily living , psychological function and social function (p=0.05). There was no statistically significant association between functional status and sociodemographic, clinical variables (p=0.05).The present study demonstrated that selected strengthening exercises are effective in improving functional status among patients with Chronic Kidney Disease.