1. How to submit my research paper? What’s the process of publication of my paper?
The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or.pdf format to the submission email: ijpmbs@ejournal.net.
You’ll be given a paper number if your submission is successful. Your paper then will undergo peer review process, which may take approximately one and a half months under normal circumstances, three tops.
After blind peer review, you will receive the notification letter with the review result of your paper...
2. Can I submit an abstract?
The journal publishes full research papers.[Read More]
 

A Superior Drug in Treating Sports Injury: A Comparative Study of Flupiritine with Combination of Aceclofenac and Tizanidine in Musculoskeletal Pain

Bijay Kumar and P K Agarwal
Department of Pharmacology, Rama Medical College- Hospital & Research Centre, Mandhana, Kanpur 209217 (UP).
Abstract—Wrist, ankle and knee sprains are most commonly encountered problems in sports. In these cases pain relief and functional restoration at the earliest are the management goals. One of the most preferred drug treatment for pain control by Orthopedician in our area is a combination of Aceclofenac and Tizanidine despite their intolerable ADR profile. Flupiritine is a relatively newer class of drug having excellent analgesic and musculoskeletal relaxant property and with an excellent safety profile. This prospective, randomized, open label, active control trial was conducted with 200 participants having sprain who were prescribed either a combination of Aceclofenac 100 mg and Tizanidine 2 mg twice daily or Flupiritine 100 mg twice daily orally. Follow up was done on day 2, 4 and 7 with numeric rating scale, verbal descriptor scale and faces pain scale. Participant receiving Flupiritine experienced better pain relief and less disability (36%) than that of those receiving a combination of Aceclofenac and Tizanidine (11%) on day 2. After a week therapy 88% of participants reported complete pain relief with Flupiritine compared to only 51% with a combination of Aceclofenac and Tizanidine ( p value < 0.001). ADR was much less in Flupiritine group (1%) compared to combination of Aceclofenac and Tizanidine (7%).

Index Terms—Sprain, Flupiritine, Analgesic, Muscle relaxant

Cite: Bijay Kumar and P K Agarwal, "A Superior Drug in Treating Sports Injury: A Comparative Study of Flupiritine with Combination of Aceclofenac and Tizanidine in Musculoskeletal Pain," International Journal of Pharma Medicine and Biological Sciences, Vol. 3, No. 3, pp. 146-151, July 2014.
Copyright © 2012-2020 International Journal of Pharma Medicine and Biological Sciences, All Rights Reserved
E-mail: ijpmbs@ejournal.net