Abstract—Aim: This study was carried out to determine the level of platelet and fibrinogen in diabetic patients. Materials and Method: 50 diabetic patients within the age of 35 and 65 years attending clinic at federal Medical Centre Owerri, were used as test subject in the determination of platelet and fibrinogen levels in diabetic patient while the control subjects are of the same age bracket and population but non-diabetic patients. Results: The results show that the level of platelet count in diabetic patients (134.2 ± 18.9 mmx10/L) was significantly (p<0.05) lower when compared with the control patients (404.8 ± 57.2 mmx10/L). Also, the level of fibrinogen in diabetics (6.30 ± 0.939 g/L) was significantly (p<0.05) higher when compared with the control (2.51 ± 0.35 g/L), Conclusion: This shows that platelets is reduced while fibrinogen is increased in diabetics and could be probably cause delayed process in wound healing in diabetic patient.