Abstract—The present study was carried out to evaluate the effect of Methanol Extract of Green Tea (MEGT) on Tumor growth and haematological parameters. After inoculation of DAL cells in to mice, treatment with MEGT (200 and 400 mg/kg) and standard drug 5-Fluorouracil (10 mg/kg) were continued for 9 days. The MEGT decreased the ascites fluid volume, viable cell count, and increased the non viable cell count. RBC, WBC, PCV, Haemoglobin content and differential count was estimated from the peripheral blood of normal, DAL control and extract treated animal groups. Haemoglobin and RBC level that generally goes down during the progression of tumor was found to improve in mice treated with MEGT. The total WBC counts which were significantly higher in the DAL control mice was found to be reduced in treated groups. This indicates that MEGT possesses protective action on the haemopoietic system. In short, the present work indicates that the MEGT exhibited significant effect on Tumor growth and haematological parameters against DAL cell lines.