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The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or.pdf format to the submission email: ijpmbs@ejournal.net.
You’ll be given a paper number if your submission is successful. Your paper then will undergo peer review process, which may take approximately one and a half months under normal circumstances, three tops.
After blind peer review, you will receive the notification letter with the review result of your paper...
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The journal publishes full research papers.[Read More]
 

Recent Advances in Mucoadhesive/Bioadhesive Drug Delivery System: A Review

Phanindra B, B Krishna Moorthy, and M Muthukumaran
Montessori Siva Sivani Institute of Science&Technology College of Pharmacy, Mylavaram, Vijayawada, Andhra Pradesh-521230.
Abstract—The current article has been focused on the mucoadhesive drug delivery system may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release for improved therapeutic outcome. Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Application of dosage forms to mucosal surfaces may be of benefit to drug molecules not amenable to the oral route, such as those that undergo acid degradation or extensive first-pass metabolism. The mucoadhesive ability of a dosage form is dependent upon a variety of factors, including the nature of the mucosal tissue and the physicochemical properties of the polymeric formulation. This review article aims to provide an overview of the various aspects of mucoadhesion, mucoadhesive materials, factors affecting mucoadhesion, evaluating methods, and finally various mucoadhesive drug delivery systems (buccal, nasal, ocular, gastro, vaginal, and rectal) based on literatures were reported so far.

Index Terms—Bioadhesive, Transmucosal, Bioavailability, Transdermal

Cite: Phanindra B, B Krishna Moorthy, and M Muthukumaran, "Recent Advances in Mucoadhesive/Bioadhesive Drug Delivery System: A Review," International Journal of Pharma Medicine and Biological Sciences, Vol. 2, No. 1, pp. 68-84, January 2013.
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