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Seroprevalence of Syphilis in HIV Patients

Kiran Bala, Uma Chaudhary, P S Gill, Seema Mittal, and Prakriti Vohra
Pt. BD Sharma, PGIMS, Rohtak.
Abstract—It is known that history of any sexually transmitted disease (STD), including syphilis, is associated with an increased risk of Human immunodeficiency Virus (HIV) infection among both homosexuals and heterosexuals. Serological surveys continue to be the best source of information on the prevalence of syphilis. Venereal Disease Research Laboratory (VDRL) test is a useful screening test to determine seroprevalence of syphilis in a community. MATERIAL AND METHODS- This retrospective study was conducted in the department of Microbiology of Pt. B.D. Sharma, PGIMS, Rohtak. A total of 61,140 serum samples received in the laboratory, from July 2008 to July 2012. RESULTS- Out of 61,140 serum samples, 1735 (2.8%) were VDRL reactive. VDRL reactivity in HIV non reactive serum samples was 2.96% in 2008, 3.0% in 2009, 2.9% in 2010, 2.8% in 2011 and 2.8% in 2012 respectively. VDRL reactivity was found to be maximum among HIV reactive males in which a rising titre was observed. CONCLUSION- Prevalence of syphilis is more in HIV infected population as compared to HIV non infected population.

Index Terms—HIV, Seroprevalence, STD, Syphilis, VDRL

Cite: Kiran Bala, Uma Chaudhary, P S Gill, Seema Mittal, and Prakriti Vohra, "Seroprevalence of Syphilis in HIV Patients," International Journal of Pharma Medicine and Biological Sciences, Vol. 2, No. 1, pp. 38-44, January 2013.
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