Abstract—Rubber tapping causes various health problems among rubber tapping workers. It varies from simple musculoskeletal aches to more serious and complicated structural damage to bone, muscles, tendons and nerves of musculoskeletal system. The present study was conducted in rubber tapping workers in two districts of Kerala. A total of 343 rubber tapping workers were included and 246 subjects with same socio economic status and equivalent physical activity workers were elected as control subject. The most common affected body region among respondents was neck pain (NP) (72.2%) followed by low back pain (66.2%), shoulders pain (44.9%), knee pain (55.8%), ankles/feet pain (34.4%), elbow pain (33.2%), upper back pain (30.8%), wrists pain (50.1%) and hip/thighs pain (15.3%). Boarder line significant difference was observed in the alteration of lung function in rubber tappers and controls. The study revealed that the workers were in potential risk of neck pain and various other musculo skeletal diseases (MSD) and lung function abnormalities due to exposure to acids, which are being used for the coagulation of latex.