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Prevalence of Typhoid and Paratyphoid, in Relation To Their Genotype among Student of Novena University, Ogume

Otoikhian C S O and Okoror L E
Novena University, College of Natural And Applied Sciences, Department of Biological Sciences, P.M.B. 2, Kwale-ogume, Delta State, Nigeria.
Abstract—Blood samples and records of patients were sourced from health centre and hospitals around Ukwani local government area as well as Novena University health clinic to assess the susceptibility to typhoid/ paratyphoid fever according to blood group system. Commercially available anti-A and anti-B blood grouping reagent as well as antigen ¡®O¡¯ and ¡®H¡¯ antigen for Salmonellae paratyphi A, the ¡®O¡¯ and ¡®H¡¯ antigen for S. paratyphi B and Salmonellae group antigen phase 211 for S. typhimurium were employed in this study. Result of the study reveals 60(60%) of the hundred (100) blood samples were infected with typhoid/ paratyphoid fevers and that 20(20%) and 50(50%) of the 100 blood samples belonged to blood group A, B, AB, and O respectively. Bacteremia was higher among females (38%) than males (22%). The highest typhoid/paratyphoid attack was observed among blood group O 46(46%) whereas the least was noticed among blood group AB individual 2 (2%). Results have revealed a possible association between ABO blood group system and susceptibility to typhoid/paratyphoid infections.

Index Terms—Typhoid, Paratyphoid, Genotype, O and H antigen

Cite: Otoikhian C S O and Okoror L E, "Prevalence of Typhoid and Paratyphoid, in Relation To Their Genotype among Student of Novena University, Ogume," International Journal of Pharma Medicine and Biological Sciences, Vol. 1, No. 2, pp. 217-224, October 2012.
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