Abstract—The glycemic response of processed amaranth grains were assessed using fifty Non Insulin Dependent Diabetes Mellitus (NIDDM) subjects. The post-prandial serum glucose concentration over a period of 2 h were determined half hourly, after the ingestion of the experimental diets. Blood glucose curves were constructed to calculate the glycemic index of the test foods. The results revealed that the Glycemic Indices (GI) of Roasted Amaranth Grains Flour Chapatti (RAGFC), Boiled Amaranth Grains Flour Chapatti (BAGFC), Popped Amaranth Grains Flour Chapatti (PAGFC) and Raw Amaranth Grains Flour Chapatti (RaAGFC) did not showed any differences at ( p \< 0.05). However, popped amaranth grains flour Chapatti gave the lowest glycemic index and the value was significantly lower than the other test foods. The popped amaranth grains flour elicit low postprandial rise of blood glucose and can be recommended for use in the diet of diabetic Indians.