Abstract—Effect of flaxseeds supplementation on serum lipid profile of selected hypercholesteremic patients was studied. Flaxseeds were processed (roasted) and analysed for its nutritional and fatty acid profile and incorporated into chapattis (15gms) and evaluated organoleptically. Administration of roasted Flaxseed powder of 15 gm for 4 weeks produces significant (P\<0.001) reduction of serum total cholesterol, triglyceride, LDL-cholesterol and increase serum HDL cholesterol in hyperlipidemic group. On the other hand, changes of lipid profile in hypercholesteremic patients without roasted Flaxseeds incorporated were not significant (P\<0.001). The present study suggests that roasted Flaxseeds powder incorporated would be considered as effective agent for lipid lowering purposes.