Abstract—The aim of the article is to present a case of pathological fracture which on evaluation by histopathology and immunohistochemistry was due to adenocarcinoma of lung. The skeletal system is the third most common site to be involved by metastatic tumor after the lungs and liver. By far the most common location for osseous metastases is the axial skeleton, followed by proximal femur and proximal humerus. Fractures after a minor or insignificant injury should always raise the suspicion of an underlying lesion. Sincepatients with more aggressive tumor types (lung) have a much shorter life expectancy than those with less aggressive types (prostate), early diagnosis and treatment is essential.